First formed in the early '50s, the Isley Brothers enjoyed one of the longest, most influential, and most diverse careers in the pantheon of popular music -- over the course of nearly a half century of performing, the group's distinguished history spanned not only two generations of Isley siblings but also massive cultural shifts which heralded their music's transformation from gritty R&B to Motown soul to blistering funk. The first generation of Isley siblings was born and raised in Cincinnati, OH, where they were encouraged to begin a singing career by their father, himself a professional vocalist, and their mother, a church pianist who provided musical accompaniment at their early performances. Initially a gospel quartet, the group was comprised of Ronald, Rudolph, O'Kelly, and Vernon Isley; after Vernon's 1955 death in a bicycling accident, tenor Ronald was tapped as the remaining trio's lead vocalist. In 1957, the brothers went to New York City to record a string of failed doo wop singles; while performing a spirited reading of the song "Lonely Teardrops" in Washington, D.C., two years later, they interjected the line "You know you make me want to shout," which inspired frenzied audience feedback. An RCA executive in the audience saw the concert, and when he signed the Isleys soon after, he instructed that their first single be constructed around their crowd-pleasing catch phrase; while the call-and-response classic "Shout" failed to reach the pop Top 40 on its initial release, it eventually became a frequently covered classic.